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Beyond Trauma: Danger Mode, Energy Conservation, and the Architecture of Regulation
Toward a neurodiversity-affirming model of allostasis, salience, interoception, and environmental mismatch Trauma matters. For many people, trauma is one of the clearest names we have for how the past keeps living in the body. Trauma-informed… Read more
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Atypicality Is Not Dysfunction: What Stress Biology Can Teach Autism Research
Autism research often begins with a familiar comparison: autistic people are measured against non-autistic controls. Researchers observe differences in gaze, social timing, sensory response, movement, attention, emotion recognition, interoception, or stress physiology. Those differences are… Read more
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From Precision Parts to Precision Systems
Personalized medicine keeps almost arriving. Here is the level it has been missing — and why the science of neurodiversity is where it gets found. There is an adventure science set aside almost before it… Read more
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INSAR Holes: A Systems Science of Autism?
A discussion essay follow-up to “What Biology Came Back to INSAR” mapping the complexity, dynamics, and regulation research already underway — and asking where this science should convene. Note: This blog post is a work… Read more
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Which Biology Came Back to INSAR?
A response to “Bringing basic biology back to INSAR,” The Transmitter, 28 May 2026 This week, May 28th, 2026, The Transmitter ran a Q&A with Christine Wu Nordahl, scientific chair of INSAR 2026 in Prague,… Read more
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Cancer Through the ESF Lens: Why Architectural Heterogeneity Matters
A complexity-informed perspective on why cancer heterogeneity may reflect not only tumor biology, but differences in host regulatory architecture Most cancer models still center the lesion: what mutation, what carcinogen, what pathway, what exposure. Those… Read more
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Flatland and the Ocean: Why Behavioral Models Break Down at Sea
The New York Times just published a piece called “Short Naps, Long Hours: How Autism Clinics Squeeze Medicaid Dollars Out of Preschoolers” (Ghorayshi, May 23, 2026). It follows months of Wall Street Journal investigations exposing… Read more
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The Emergent Paradigm: Why Medicine Keeps Hitting the Same Wall
A bridge essay on the historical, conceptual, and structural shift toward adaptive medicine Lori Hogenkamp | Center for Adaptive Stress | evostress.blog For years, medicine has looked increasingly uncertain about the conditions affecting the largest… Read more
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Stop Splitting Diagnoses. Start Splitting Medicine.
A companion to: “If We Did Split the Spectrum: What Would It Actually Require?” Lori Hogenkamp | Center for Adaptive Stress | evostress.blog The autism spectrum is fragmenting under the weight of its own heterogeneity.… Read more
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If We Did Split the Spectrum: What Would It Actually Require?
A companion to: “The Autism Spectrum Isn’t Collapsing. The Model Is. We Just Don’t See It Yet.” Lori Hogenkamp | Center for Adaptive Stress | evostress.blog Over the past several months, a growing number of… Read more
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